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产品简介
| 英文名称 | Anti-C4BPB Polyclonal Antibody |
| 别名 | C4BP;C4b-binding protein beta chain; |
| 宿主 | Rabbit |
| 稀释比例 | IHC 1:50-200. |
| Gene ID | 725 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P20851 |
| 蛋白分子量 | 28kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | A synthetic peptide ofHuman C4BPB |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. |
| Public Immunogen Range | 110-160/252aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanPredicted:CowRatMouse |
| 应用 | IHC |
| 规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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