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产品简介
| 英文名称 | Anti-UCP1 Polyclonal Antibody |
| 别名 | SLC25A7;Thermogenin;UCP;UCP1;UCP1 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-1000. IHC 1:20-200. |
| Gene ID | 7350 |
| 保存 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
| Swiss Prot | P25874 |
| 蛋白分子量 | 33kDa |
| 储存液 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| 亚细胞定位 | Membrane Mitochondrion Mitochondrion inner membrane |
| 免疫原 | Recombinant fusion protein of Human UCP1 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates in non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance (By similarity). Functions as a long-chain fatty acid/LCFA and proton symporter, simultaneously transporting one LCFA and one proton through the inner mitochondrial membrane (PubMed:24196960). However, LCFAs remaining associated with the transporter via their hydrophobic tails, it results in an apparent transport of protons activated by LCFAs. Thereby, dissipates the mitochondrial proton gradient and converts the energy of substrate oxydation into heat instead of ATP. Regulates the production of reactive oxygen species/ROS by mitochondria (By similarity). |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | IHCELISAWB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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