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产品简介
| 英文名称 | Anti-SNX17 Polyclonal Antibody |
| 别名 | KIAA0064 |
| 宿主 | Rabbit |
| 稀释比例 | IHC 1:100-300. |
| Gene ID | 9784 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q15036 |
| 蛋白分子量 | 50/53kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | Recombinant protein of Human SNX17 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Critical regulator of endosomal recycling of numerous surface proteins, including integrins, signaling receptor and channels. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Associates with retriever and CCC complexes to prevent lysosomal degradation and promote cell surface recycling of numerous cargos such as integrins ITGB1, ITGB5 and their associated alpha subunits. Also required for maintenance of normal cell surface levels of APP and LRP1. Interacts with membranes containing phosphatidylinositol 3-phosphate. |
| Public Immunogen Range | 1-350aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | IHC |
| 规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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