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产品简介
| 英文名称 | Anti-ANXA7 Polyclonal Antibody |
| 别名 | Annexin A7; Annexin VII; Annexin-7; ANX7; ANXA7; ANXA7_HUMAN; SNX; Synexin; |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:8000-12000. |
| Gene ID | 310 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P20073 |
| 蛋白分子量 | 50/53kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm? Nucleus |
| 免疫原 | Recombinant protein of human ANXA7 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to geneRate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion. |
| Public Immunogen Range | 1-350aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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