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产品简介
| 英文名称 | Anti-ARRB2 Polyclonal Antibody |
| 靶标 | STK38 |
| 别名 | ARRB2;ARB2;ARR2;BARR2 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:1000-3000. IHC 1:50-200. |
| Gene ID | 409 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P32121 |
| 蛋白分子量 | 44/46/47/48kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Nucleus Cell membrane |
| 免疫原 | A synthetic peptide of ARRB2 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Public Immunogen Range | 1-51/409aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanPredicted:CowRatMouse |
| 应用 | WBIHC |
| 规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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