暂无数据
产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
-
Anti-AF-6（B-5） Monoclonal AntibodyAGV-K009780M-1ml￥ 4300.001
产品简介
| 英文名称 | Anti-AF-6（B-5） Monoclonal Antibody |
| 靶标 | ARRB1 |
| 别名 | AF 6; AF6; AFAD_HUMAN; Afadin; ALL1-fused gene from chromosome 6 protein; FLJ34371; MLLT 4; MLLT4; Myeloid/lymphoid or mixed lineage leukemia (trithorax homolog Drosophila) translocated to 4; Myeloid/lymphoid or mixed lineage leukemia translocated to 4; Protein AF 6; Protein Af-6; Protein AF6; RP3 431P23.3; 5033403D15Rik; Gm314; I-afadin; Mllt4; S-afadin. |
| 宿主 | Rabbit |
| 稀释比例 | WB?1:100- 1:1000. IP 1-2 μg per 100-500 μg of total protein (1 ml of cell lysate).?IF ?1:50-1:500. IHC 1:50-1:500. ELISA 1:30-1:3000 |
| Gene ID | 4301 |
| 保存 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
| Swiss Prot | P55196 |
| 蛋白分子量 | 207kDa |
| 储存液 | PBS with < 0.1% sodium azide and 0.1% gelatin. |
| 亚细胞定位 | Cell membrane |
| 免疫原 | Recombinant fusion protein of Human AF-6 |
| 亚型 | IgG2aK |
| 纯化方法 | Affinity purification |
| 克隆号 | B-5 |
| 背景资料 | The dynamics of a cell-cell interface such as tight junctions or adherensjunctions are important in many developmental, physiological and pathological processes. AF-6 (MLLT4: myeloid/lymphoid or mixed-lineage leukemia translocated to 4) is a 1,612 amino acid protein that contains two N-terminal Ras binding domains (RBD) and a GLGF motif, and is implicated in Ras-mediated signaling events occurring at peripheral cell-cell junctions. AF-6 interacts with F-Actin and Profilin in cell-cell junctions, and may modulate Actin modeling near adhesion complexes. Furthermore, AF-6 coordinates junction adhesion molecule (JAM) recruitment to intercellular junctions through a PDZ domain. Developing mice deficient in AF-6 activity display a loss of neuroepithelial polarity, suggesting that AF-6 activity is an important regulator of cell-cell junctions that influence apical/basolateral asymmetry |
| 克隆类型 | Monoclonal antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WBELISAIHC-PIFIP |
| 规格 | 1ml |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
暂无数据
我要询价
*联系方式：
(可以是QQ、MSN、电子邮箱、电话等，您的联系方式不会被公开)
*内容：
