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产品简介
| 英文名称 | Anti-EMR1 Polyclonal Antibody |
| 靶标 | 靶标 |
| 别名 | ADGRE1, Adhesion G protein-coupled receptor E1, EGF like module receptor 1, EMR1, EMR1 hormone receptor, F4/80, TM7LN3 |
| 稀释比例 | WB : 1:200-1000. IHC 1:50-500. |
| Gene ID | 2015 |
| 保存 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
| Swiss Prot | Q14246 |
| 蛋白分子量 | 90kDa |
| 储存液 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| 亚细胞定位 | Cell membrane Multi-pass membrane protein |
| 免疫原 | Recombinant fusion protein of Human EMR1 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | EMR1 (EGF-like module containing mucin-like hormone receptor 1), also known as Adhesion G protein-coupled receptor E1 (ADGRE1), is a surface receptor with seven transmembrane segments that belongs to the EGF-7-transmembrane family of G protein-coupled receptors (PMID: 14647991, 7601460). EMR1 expression is restricted to eosinophilic granulocytes, where expression is overlapping with the eotaxin receptor CCR3 and the immunoglobulin-like lectin Siglec-8. Absence on other leukocytes, including basophils, implies that EMR1 is a highly specific marker for eosinophils in humans and may be used as a novel therapeutic target for eosinophilic disorders(PMID: 17823986, 24530099). F4/80, the murine homolog of EMR1, is a marker of murine macrophage. The apparent molecular weigh of F4/80 is 160 kDa, which is lager than the calculated molecular weight due to post-translational modifications (PMID: 7308288; 8647179). |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanMouse |
| 应用 | WBELISAIHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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