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产品简介
| 英文名称 | Anti-ST6GALNAC6 Polyclonal Antibody |
| 靶标 | ST6GALNAC6 |
| 别名 | FLJ13669;FLJ27239;GalNAc alpha-2,6-sialyltransferase III;PRO7177 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:5000-8000. |
| Gene ID | 30815 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q969X2 |
| 蛋白分子量 | 34/38/41kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | Recombinant protein of human ST6GALNAC6 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Transfers the sialyl group (N-acetyl-alpha-neuraminyl or NeuAc) from CMP-NeuAc onto glycoproteins and glycolipids, forming an alpha-2,6-linkage. Produces branched type disialyl structures by transfer of a sialyl group onto the GalNAc or GlcNAc residue inside backbone core chains having a terminal sialic acid with an alpha-2,3-linkage on Gal. ST6GalNAcVI prefers glycolipids to glycoproteins, predominantly catalyzing the biosynthesis of ganglioside GD1alpha from GM1b (PubMed:12668675, PubMed:17123352). Besides GMb1, MSGG and other glycolipids, it shows activity towards sialyl Lc4Cer generating disialyl Lc4Cer, which can lead to the synthesis of disialyl Lewis a (Le(a)), suggested to be a cancer-associated antigen (PubMed:12668675). Also has activity toward GD1a and GT1b, and can generate DSGG (disialylgalactosylgloboside) from MSGG (monosialylgalactosylgloboside) (By similarity). |
| Public Immunogen Range | 61-333aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanPredicted:BovineMouse |
| 应用 | WB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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