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产品简介
| 英文名称 | Anti-BAX Polyclonal Antibody |
| 靶标 | BAX |
| 别名 | BCL2L4;Bcl2-L-4;Bcl-2-like protein 4;Apoptosis regulator BAX; |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:1000-3000. |
| Gene ID | 581 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q07812 |
| 蛋白分子量 | 5/13/16/18/19/20/21/24kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Cell membrane |
| 免疫原 | Recombinant protein of human BAX |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Plays a role in the mitochondrial apoptotic process. Under normal conditions, BAX is largely cytosolic via constant retrotranslocation from mitochondria to the cytosol mediated by BCL2L1/Bcl-xL, which avoids accumulation of toxic BAX levels at the mitochondrial outer membrane (MOM) (PubMed:21458670). Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. |
| Public Immunogen Range | 1-192aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanPredicted:BovineRatMouse |
| 应用 | WB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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