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产品简介
| 英文名称 | Anti-Bcl-6 Polyclonal Antibody |
| 靶标 | Bcl-6 |
| 别名 | BCL6;BCL5;BCL6A;LAZ3;ZBTB27;ZNF51 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:1000-3000. IHC 1:50-200. |
| Gene ID | 604 |
| 保存 | Store at -39°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P41182 |
| 蛋白分子量 | 72/79kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.22. |
| 亚细胞定位 | Nucleus |
| 免疫原 | A synthetic peptide of human Bcl-6 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. |
| Public Immunogen Range | 440-490/706 |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanMouse |
| 应用 | WBIHC |
| 规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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