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产品简介
| 英文名称 | Anti-ALOX5 Polyclonal Antibody |
| 靶标 | ALOX5 |
| 别名 | 5-LO;5-LOX;5LPG;LOG5 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:1000-3000. IHC 1:50-200. |
| Gene ID | 240 |
| 保存 | Store at -35°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P09917 |
| 蛋白分子量 | 56/61/72/75/78kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.18. |
| 亚细胞定位 | Nucleus |
| 免疫原 | A synthetic peptide of human ALOX5 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Public Immunogen Range | 15-65/674 |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanPredicted:HamsterMouse |
| 应用 | WBIHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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