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产品简介
| 英文名称 | Anti-APLP2 Polyclonal Antibody |
| 靶标 | APLP2 |
| 别名 | APLP2;APLP-2;APPH;APPL2;CDEBP |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:1000-3000. IHC 1:50-200. |
| Gene ID | 334 |
| 保存 | Store at -25°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q06481 |
| 蛋白分子量 | 59/79/81/85/87kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.8. |
| 亚细胞定位 | Secreted Nucleus |
| 免疫原 | A synthetic peptide of human APLP2 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. |
| Public Immunogen Range | 713-763/763 |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WBIHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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