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产品简介
| 英文名称 | Anti-PNN Polyclonal Antibody |
| 靶标 | PNN |
| 别名 | PNN;DRS;DRSP;SDK3;memA;pinin |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:1000-3000. IHC 1:100-300. |
| Gene ID | 5411 |
| 保存 | Store at -60°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q9H307 |
| 蛋白分子量 | 82kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.43. |
| 亚细胞定位 | Nucleus |
| 免疫原 | A synthetic peptide of human PNN |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5'CAGGTG-3'. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulation of alternative pre-mRNA splicing. Associates to spliced mRNA within 60 nt upstream of the 5'-splice sites. Component of the PSAP complex which binds RNA in a sequence-independent manner and is proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets. Involved in the establishment and maintenance of epithelia cell-cell adhesion. Potential tumor suppressor for renal cell carcinoma. |
| Public Immunogen Range | 395-445/717 |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanPredicted:Cow,Chimpanzee,DogMouse |
| 应用 | WBIHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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