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产品简介
| 英文名称 | Anti-CD86(PE)Monoclonal Antibody |
| 靶标 | CD86 |
| 别名 | B7, B7 2, B7.2, B70, Cd28l2, Cd86, CD86 antigen, CLS1, ETC 1, Ly 58, Ly58, MB7, MB7 2, TS/A 2 |
| 宿主 | Rat |
| 稀释比例 | FCM:10^6cells加0.13ug |
| Gene ID | 12524 |
| 保存 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
| 储存液 | PBS with 0.1% sodium azide and a stabilizer. |
| 亚细胞定位 | Cell membrane |
| 亚型 | IgG2a |
| 纯化方法 | Affinity purification |
| 背景资料 | CD86 (also known as B7-2) is a costimulatory molecule belonging to the immunoglobulin superfamily. Primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, and macrophages, CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and CTLA-4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with CTLA-4 negatively regulates T-cell activation and diminishes the immune response. (PMID: 7513726; 1847722; 11029388; 27591335) |
| 克隆类型 | Monoclonal antibody |
| 交叉反应 | Mouse |
| 规格 | 25ug100ug |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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