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产品简介
| 英文名称 | Anti-Neuropilin 1 Monoclonal Antibody |
| 靶标 | Neuropilin 1 |
| 别名 | BDCA4, CD304, neuropilin 1, NRP, NRP1, VEGF165R |
| 宿主 | Mouse |
| 稀释比例 | WB : 1:1000-1:6000. IF : 1:50-1:500. FCM :0.2μg/Test. |
| Gene ID | 8829 |
| 保存 | Store at -20℃. Avoid freeze / thaw cycles. |
| Swiss Prot | O14786 |
| 蛋白分子量 | 103kDa |
| 储存液 | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
| 亚细胞定位 | Cell membrane Secreted Single-pass type I membrane protein |
| 免疫原 | Recombinant protein of human Neuropilin 1 |
| 亚型 | IgG1 |
| 纯化方法 | Affinity purification |
| 背景资料 | Neuropilin-1 (NRP1) is a a 130-140 kDa transmembrane glycoprotein expressed by endothelial, dendritic, and regulatory T cells, as well as several other normal cell types and malignant tumor cells. NRP1 was first identified as a semaphorin (SEMA) receptor, involved in axonal guidance in embryonic development. NRP1 was also shown to act as a receptor for vascular endothelial growth factor (VEGF) and a promoter of angiogenesis through its interaction with VEGF-A165 (and other VEGFs) and the receptor tyrosine kinase (RTK) VEGF-R2. NRP1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration, and invasion. |
| 克隆类型 | Monoclonal antibody |
| 交叉反应 | Humanpig |
| 应用 | WBELISAIFFC |
| 规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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