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产品简介
靶标 | Casein Kinase 1 alpha |
别名 | CK1; CK1a; CKIa; HEL-S-77p; HLCDGP1; PRO2975 |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. IHC 1:50-200. |
Gene ID | 1452 |
保存 | Store at -20℃. Avoid freeze / thaw cycles. |
Swiss Prot | P48729 |
蛋白分子量 | 35kDa |
储存液 | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
亚细胞定位 | Chromosome Cytoplasm Nucleus speckle centromere centrosome cytoskeleton kinetochore microtubule organizing center |
免疫原 | A synthesized peptide derived from human Casein Kinase 1 alpha |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis (PubMed:11955436, PubMed:1409656, PubMed:18305108).May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration (PubMed:23902688). |
克隆类型 | Monoclonal antibody |
交叉反应 | HumanRatMouse |
应用 | WBIHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
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