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产品简介
| 靶标 | MLKL |
| 别名 | FLJ34389, MLKL |
| 宿主 | Mouse |
| 稀释比例 | WB 1:2000-10000. IHC 1:500-2000. IF 1:50-500 |
| Gene ID | 197259 |
| 保存 | Store at -20℃. Avoid freeze / thaw cycles. |
| Swiss Prot | Q8NB16 |
| 蛋白分子量 | 54kDa |
| 储存液 | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
| 亚细胞定位 | Cell membrane Cytoplasm |
| 免疫原 | Recombinant protein of human MLKL. |
| 亚型 | IgG1 |
| 纯化方法 | Affinity purification |
| 背景资料 | Mixed lineage kinase domain like pseudokinase (MLKL), belongs to the protein kinase superfamily, has two MW of 54 and 30 kDa. MLKL plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. 66675-1-Ig antibody recognizes 54 kDa MLKL monomer, 216 kDa MLKL tetramer and a band around 45-50 kDa which are similar to papers published. (PMID: 31848291) |
| 克隆类型 | Monoclonal antibody |
| 交叉反应 | HumanMouse |
| 应用 | WBELISAIFIHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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