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产品简介
靶标 | DCX/Doublecortin |
别名 | Doublecortex; DBCN; Dbct; DC; Doublin; Lis X; Lissencephalin X; Lissencephaly X linked;Lissencephaly X linked doublecortin; LISX; Neuronal migration protein doublecortin; SCLH; XLIS |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. ELISA 1:5000-10000. IHC-P 1:100-500. IHC-F 1:100-500. IF 1:50-200. |
Gene ID | 1641 |
保存 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
Swiss Prot | O43602 |
蛋白分子量 | 49kDa |
储存液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
亚细胞定位 | Cytoplasmic |
免疫原 | KLH conjugated synthetic peptide derived from human DCX |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | Doublecortin (DCX) is a microtubule-associated protein expressed almost exclusively in immature neurons. Neuronal precursors begin to express DCX shortly after exiting the cell cycle, and continue to express DCX for 2-3 weeks as the cells mature into neurons. Downregulation of DCX begins after 2 weeks, and occurs at the same time that these cells begin to express, a marker for mature neurons. Due to the nearly exclusive expression of DCX in developing neurons, this protein has been used increasingly as a marker for neurogenesis. Indeed, the levels of DCX expression increase in response to exercise, which occurs in parallel with increased BrdU labelling, currently a gold standard in measuring neurogenesis. |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WBIFIHC-FIHC-PELISA |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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