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产品简介
靶标 | ADGRE5(Cleaved-Leu530) |
别名 | ADGRE5;CD97;TM7LN1 |
宿主 | Rabbit |
稀释比例 | IHC 1:100-300. |
Gene ID | 976 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P48960 |
蛋白分子量 | 82/87/92kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Secreted Cell membrane |
免疫原 | A synthetic peptide of human ADGRE5(Cleaved-Leu530) |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. |
Public Immunogen Range | 495-545/835aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanPredicted:Cow Dog |
应用 | IHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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