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产品简介
靶标 | HIF1A |
别名 | HIF1A;HIF-1-alpha;HIF-1A;HIF-1alpha;HIF1;HIF1-ALPHA;MOP1;PASD8;bHLHe78 |
宿主 | Rabbit |
稀释比例 | IHC 1:100-300. |
Gene ID | 3091 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q16665 |
蛋白分子量 | 83/93/96kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasm Nucleus |
免疫原 | A synthetic peptide of human HIF1A |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. |
Public Immunogen Range | 520-570/826aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanPredicted:Cow ChickenRatMouse |
应用 | IHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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