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产品简介
| 靶标 | SHLD2 |
| 别名 | bA163M19.1; FA35A_HUMAN; FAM35A; FAM35A1; Family with sequence similarity 35 member A; Hypothetical protein LOC54537; MGC5560; Protein FAM35A; |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:1000-3000. IHC 1:50-200. |
| Gene ID | 54537 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q86V20 |
| 蛋白分子量 | 94/102kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | A synthetic peptide of human SHLD2 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs) (PubMed:29656893, PubMed:29789392). During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection (PubMed:29656893, PubMed:29789392). Mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination, and fusion of unprotected telomeres (PubMed:29656893). |
| Public Immunogen Range | 270-320/835aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanPredicted:Chimpanzee |
| 应用 | WBIHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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