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产品简介
| 靶标 | MSH4 |
| 别名 | MSH4 |
| 宿主 | Rabbit |
| 稀释比例 | IHC 1:100-300. |
| Gene ID | 4438 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | O15457 |
| 蛋白分子量 | 105kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Nucleus |
| 免疫原 | A synthetic peptide of human MSH4 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair. |
| Public Immunogen Range | 95-145/936aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human |
| 应用 | IHC |
| 规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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