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产品简介
| 靶标 | KLHDC4 |
| 别名 | DKFZp434G0522; FLJ00104; Kelch domain containing protein 4. KLDC4_HUMAN |
| 宿主 | Rabbit |
| 稀释比例 | IHC 1:50-200. |
| Gene ID | 54758 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q8TBB5 |
| 蛋白分子量 | 51/54/58kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | Recombinant protein of human KLHDC4 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | KLHDC4 is a 520 amino acid protein that contains six kelch repeats and exists as three alternatively spliced isoforms. The gene encoding KLHDC4 maps to human chromosome 16q24.2 and mouse chromosome 8 E1. Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. |
| Public Immunogen Range | 171-519aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanPredicted:OrangutanMouse |
| 应用 | IHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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