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产品简介
| 靶标 | RPS3 |
| 别名 | FLJ26283;FLJ27450;MGC87870;S3 |
| 宿主 | Rabbit |
| 预测交叉反应 | Cow;Pig;Dog;Chimpanzee;Fish;Xenopus;laevis |
| 稀释比例 | IHC 1:50-200. |
| Gene ID | 6188 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P23396 |
| 蛋白分子量 | 27/28kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | A synthetic peptide of human RPS3 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit, where it forms part of the domain where translation is initiated. The protein belongs to the S3P family of ribosomal proteins. Studies of the mouse and rat proteins have demonstrated that the protein has an extraribosomal role as an endonuclease involved in the repair of UV-induced DNA damage. The protein appears to be located in both the cytoplasm and nucleus but not in the nucleolus. Higher levels of expression of this gene in colon adenocarcinomas and adenomatous polyps compared to adjacent normal colonic mucosa have been observed. This gene is co-transcribed with the small nucleolar RNA genes U15A and U15B, which are located in its first and fifth introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Public Immunogen Range | 175-225/243aa |
| 克隆类型 | Polyclonal Antibody |
| 应用 | IHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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