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产品简介
| 靶标 | AP4M1 |
| 别名 | AP-4 complex subunit mu-1;AP-4 adaptor complex mu subunit;Adaptor-related protein complex 4 subunit mu-1;Mu subunit of AP-4;mu4;mu-ARP2 |
| 宿主 | Rabbit |
| 预测交叉反应 | Bovine;Dog |
| 稀释比例 | WB 1:1000-3000. |
| Gene ID | 9179 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | O00189 |
| 蛋白分子量 | 50kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | Recombinant protein of human AP4M1 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways (PubMed:10436028, PubMed:11139587, PubMed:10066790, PubMed:11802162, PubMed:20230749). AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system (PubMed:11139587, PubMed:20230749). It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons (By similarity). Within AP-4, the mu-type subunit AP4M1 is directly involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos (PubMed:10436028, PubMed:11139587, PubMed:26544806, PubMed:20230749). The adaptor protein complex 4 (AP-4) may also recognize other types of sorting signal (By similarity). |
| Public Immunogen Range | 121-360aa |
| 克隆类型 | Polyclonal Antibody |
| 应用 | WB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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