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产品简介
| 靶标 | DNASE1 |
| 别名 | DNASE1;DNL1;DRNI |
| 宿主 | Rabbit |
| 预测交叉反应 | Bovine;Pig;Rabbit;Dog;Chicken;Horse;Sheep |
| 稀释比例 | WB 1:1000-3000.;IHC 1:50-200. |
| Gene ID | 1773 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P24855 |
| 蛋白分子量 | 20/31kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Secreted Nucleus |
| 免疫原 | Recombinant protein of human DNASE1 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. |
| Public Immunogen Range | 30-283aa |
| 克隆类型 | Polyclonal Antibody |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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