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产品简介
靶标 | CYP4V2 |
别名 | BCD;CP4V2_HUMAN;CYP4AH1;CYP4V 2;CYP4V2;Cytochrome P450 4V2;Cytochrome P450, family 4, subfamily V, polypeptide 2;Retina CYP4V2;Long-chain fatty acid omega-monooxygenase;Docosahexaenoic acid omega-hydroxylase CYP4V2 |
宿主 | Rabbit |
预测交叉反应 | Orangutan |
稀释比例 | WB 1:1000-3000. |
Gene ID | 285440 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q6ZWL3 |
蛋白分子量 | 58/61kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. |
亚细胞定位 | Cytoplasm |
免疫原 | Recombinant protein of human CYP4V2 |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | A cytochrome P450 monooxygenase involved in fatty acid metabolism in the eye. Catalyzes the omega-hydroxylation of polyunsaturated fatty acids (PUFAs) docosahexaenoate (DHA) and its precursor eicosapentaenoate (EPA), and may contribute to the homeostasis of these retinal PUFAs (PubMed:22772592).Omega hydroxylates saturated fatty acids such as laurate, myristate and palmitate, the catalytic efficiency decreasing in the following order: myristate > laurate > palmitate (C14>C12>C16) (PubMed:19661213).Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). |
Public Immunogen Range | 177-526aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | Human;Mouse;Rat |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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