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产品简介
| 靶标 | BMPR2 |
| 别名 | BMP type II receptor;BMP type-2 receptor;BMPR 2;BMPR 3;BMPR II;BMPR-2;BMPR-II;Bmpr2;BMPR2_HUMAN;BMPR3;BMPRII;BMR 2;BMR2;Bone morphogenetic protein receptor type 2;Bone morphogenetic protein receptor type II;Bone morphogenetic protein receptor type-2;Bone morphogenic protein receptor type II serine threonine kinase;BRK 3;BRK3;PPH 1;PPH1;Serine threonine kinase type II activin receptor like kinase;T ALK;TALK;Type II activin receptor like kinase |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:1000-3000.;IHC 1:100-300. |
| Gene ID | 659 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q13873 |
| 蛋白分子量 | 60/115kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. |
| 亚细胞定位 | Cell membrane Secreted Nucleus |
| 免疫原 | Recombinant protein of human BMPR2 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6. |
| Public Immunogen Range | 600-950aa |
| 克隆类型 | Polyclonal Antibody |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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