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产品简介
靶标 | BACE1 |
别名 | APP beta secretase;Asp 2;ASP2;Aspartyl protease 2;BACE 1;BACE;BACE1;BACE1_HUMAN;Beta secretase 1;Beta secretase;Beta site amyloid beta A4 precursor protein cleaving enzyme;Beta site amyloid precursor protein cleaving enzyme 1;Beta site amyloid precursor protein cleaving enzyme;Beta site APP cleaving enzyme 1;Beta site APP cleaving enzyme;Beta-secretase 1;Beta-site amyloid precursor protein cleaving enzyme 1;Beta-site APP cleaving enzyme 1;FLJ90568;HSPC104;Memapsin 2;Memapsin-2;Memapsin2;Membrane associated aspartic protease 2;Membrane-associated aspartic protease 2;Transmembrane aspartic proteinase Asp2 |
宿主 | Rabbit |
预测交叉反应 | Bovine |
稀释比例 | WB 1:1000-3000.;IHC 1:50-200. |
Gene ID | 23621 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P56817 |
蛋白分子量 | 42/45/48/51/53/56kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. |
亚细胞定位 | Cytoplasm Cell membrane |
免疫原 | Recombinant protein of human BACE1 |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase (PubMed:10656250, PubMed:10677483, PubMed:20354142). |
Public Immunogen Range | 6-347aa |
克隆类型 | Polyclonal Antibody |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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