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产品简介
英文名称 | Anti-IGSF3 Polyclonal Antibody |
靶标 | IGSF3 |
别名 | EWI 3; EWI3; Glu Trp Ile EWI motif containing protein 3; Immunoglobin superfamily member 3; Immunoglobulin superfamily member 3; KIAA0466; MGC117164; V8 antibody; IGSF3_HUMAN. |
宿主 | Rabbit |
稀释比例 | WB 1:500-2000. ELISA 1:5000-10000. IHC 1:100-500. ICC 1:100-500. IF 1:50-200. |
Gene ID | 3321 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | O75054 |
蛋白分子量 | 133kDa |
储存液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
亚细胞定位 | Cell membrane |
免疫原 | A synthetic peptide of human IGSF3 |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | IGSF3, also known as V8 or EWI-3, is a 1,214 amino acid protein. Widely expressed with predominant expression in kidney, placenta and lung, IGSF3 localizes to the membrane and contains an N-terminal signal peptide, eight immunoglobulin (Ig) domains and a transmembrane segment. IGSF3 exhibits strong sequence and structural similarity to CD101 (32% identity), a leukocyte surface protein with seven Ig domains that is believed to play a role in T-cell activation. Despite the structural similarities between IGSF3 and CD101, IGSF3 is not expressed in peripheral blood lymphocytes and does not appear to participate in an immune function. Based on its subcellular localization and the presence of the eight Ig domains, IGSF3 is hypothesized to function as a surface receptor or as a cell adhesion molecule. |
克隆类型 | Polyclonal Antibody |
交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit |
应用 | WB IHC ICC IF ELISA |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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