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产品简介
| 英文名称 | Anti-DEPDC5 Polyclonal Antibody |
| 靶标 | DEPDC5 |
| 别名 | DEP domain containing 5; DEP domain-containing protein 5; DEP.5; DEPD5_HUMAN; DEPDC5; FFEVF; KIAA0645;GATOR complex protein DEPDC5;KIAA0645; |
| 宿主 | Rabbit |
| 预测交叉反应 | Fruit;fly |
| 稀释比例 | IHC 1:50-200. |
| Gene ID | 9681 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | O75140 |
| 蛋白分子量 | 64/138/171/173/179/180/181kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | Recombinant protein of human DEPDC5 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway. |
| Public Immunogen Range | 211-560 |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human;Mouse |
| 应用 | IHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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