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产品简介
英文名称 | Anti-MANF Polyclonal Antibody |
靶标 | MANF |
别名 | Arginine rich mutated in early stage tumors; Arginine rich protein; Arginine-rich protein; ARMET; ARMET protein; ARP; Manf; MANF_HUMAN; Mesencephalic astrocyte derived neurotrophic factor; Mesencephalic astrocyte-derived neurotrophic factor; MGC142148; MGC142150; Protein ARMET; |
宿主 | Rabbit |
预测交叉反应 | Bovine |
稀释比例 | IHC 1:50-200. |
Gene ID | 7873 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P55145 |
蛋白分子量 | 21kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Secreted |
免疫原 | Recombinant protein of human MANF |
亚型 | IgG |
纯化方法 | Octanoic acid-ammonium sulfate precipitation |
背景资料 | The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related. |
Public Immunogen Range | 1-183aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | Human;Mouse;Rat |
应用 | IHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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