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产品简介
| 实际分子量 | 27kDa |
| 英文名称 | Anti-OAZ3 Polyclonal Antibody |
| 靶标 | OAZ3 |
| 别名 | Antizyme 3; AZ3; OAZ t; OAZ3; OAZ3_HUMAN; ODC-Az 3; Ornithine decarboxylase antizyme 3; RP11-98D18.13-004; Testicular secretory protein Li 31; TISP15; |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:200-1000. |
| Gene ID | 51686 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q9UMX2 |
| 蛋白分子量 | 22/27kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Nucleus Cytoplasm |
| 免疫原 | Recombinant protein of human OAZ3 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimers. Does not target the ODC monomers for degradation, which allows a protein synthesis-independent restoration of ODC activity (PubMed:17900240).Stabilizes AZIN2 by interfering with its ubiquitination. Involved in the translocation of AZNI2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol. Probably plays a key role in spermatogenesis by regulating the intracellular concentration of polyamines in haploid germ cells (By similarity). |
| Public Immunogen Range | 1-191aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human;Mouse;Rat |
| 应用 | WB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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