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产品简介
| 英文名称 | Anti-ABCA8 Polyclonal Antibody |
| 靶标 | ABCA8 |
| 别名 | ABCA 8; ATP binding cassette sub family A member 8; ATP binding cassette, sub family A (ABC1), member 8;ABC-type organic anion transporter ABCA8;ATP-binding cassette sub-family A member 8;KIAA0822; |
| 宿主 | Rabbit |
| 稀释比例 | IHC 1:50-200. |
| Gene ID | 10351 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | O94911 |
| 蛋白分子量 | 31/179/184kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Cell membrane |
| 免疫原 | Recombinant protein of human ABCA8 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Catalyzes the import of organic anions such as taurocholate and estrone sulfate in an ATP-dependent manner (PubMed:12379217).In vitro, also imports ochratoxin A (PubMed:12379217).In addition mediates the cholesterol efflux in an apolipoprotein independent manner an plays a role in sphingomyelin production in oligodendrocytes (PubMed:23560799).Catalyzes the cholesterol and taurocholate efflux in an ATP-dependent manner (PubMed:29300488).Through the interaction with ABCA1 potentiates the cholesterol efflux to lipid-free APOA1, in turn regulates high-density lipoprotein cholesterol levels (PubMed:28882873). |
| Public Immunogen Range | 60-215aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human;Mouse |
| 应用 | IHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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