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产品简介
| 靶标 | GRIK5 |
| 别名 | EAA 2; EAA2; Excitatory amino acid receptor 2; GluRgamma2; Glutamate receptor; Glutamate receptor KA 2; Glutamate receptor KA-2; Glutamate receptor KA2; Glutamate receptor, ionotropic kainate 5 [Precursor]; Glutamate receptor, ionotropic, kainate 5 (gamma 2); Glutamate receptor, ionotropic, kainate 5; GRIK 2; GRIK 5; GRIK2; Grik5; GRIK5_HUMAN; iGlu5; ionotropic kainate 5; KA2; MGC118086. |
| 宿主 | Rabbit |
| 预测交叉反应 | Human;Mouse;Rat;Dog;Pig;Sheep |
| 稀释比例 | WB 1:500-2000.; IHC 1:100-500.; IF 1:100-500.;ELISA 1:5000-10000. |
| Gene ID | 2901 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q16478 |
| 蛋白分子量 | 109kDa |
| 储存液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 亚细胞定位 | Cell junction,Cell membrane,Multi-pass membrane protein,postsynaptic cell membrane,synapse |
| 免疫原 | KLH conjugated synthetic peptide derived from human GRIK5 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of the structurally related subunits GluR-1 to -7, KA1 and KA2. KA1 (also designated EEA1) and KA2 (also designated EEA2) form heteromeric receptors with GluR subunits when coexpressed, forming ion channels with various properties. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate. |
| Public Immunogen Range | 201-300/980aa |
| 克隆类型 | Polyclonal Antibody |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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