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产品简介
| 靶标 | TFB2M |
| 别名 | Hkp1;mtTFB2;N''-adenosyl(rRNA) dimethyltransferase 2; S adenosylmethionine 6 N', N' adenosyl(rRNA) dimethyltransferase 2; Dimethyladenosine transferase 2; dimethyladenosine transferase 2 mitochondrial; FLJ22661; FLJ23182; h mtTFB; h mtTFB2; h-mtTFB; h-mtTFB2; HCV NS5A transactivated protein 5; HCV NS5A-transactivated protein 5; hepatitis C virus NS5A transactivated protein 5; Hepatitis C virus NS5A-transactivated protein 5; Hkp1; hTFB2M; Mitochondrial 12S rRNA dimethylase 2; mitochondrial; Mitochondrial dimethyladenosine transferase 2; Mitochondrial transcription factor B2; mtTFB; mtTFB2; NS5ATP5; S-adenosylmethionine-6-N'; TFB2M; TFB2M_HUMAN; Transcription Factor B2; Transcription factor B2 mitochondrial; |
| 宿主 | Rabbit |
| 预测交叉反应 | Bovine |
| 稀释比例 | WB 1:1000-3000.; IHC 1:50-200. |
| Gene ID | 64216 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q9H5Q4 |
| 蛋白分子量 | 45kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | Recombinant protein of human TFB2M |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | S-adenosyl-L-methionine-dependent rRNA methyltransferase which may methylate two specific adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 12S mitochondrial rRNA (Probable). Component of the mitochondrial transcription initiation complex, composed at least of TFB2M, TFAM and POLRMT that is required for basal transcription of mitochondrial DNA.In this complex, TFAM recruits POLRMT to a specific promoter whereas TFB2M induces structural changes in POLRMT to enable promoter opening and trapping of the DNA non-template strand.Stimulates transcription independently of the methyltransferase activity. |
| Public Immunogen Range | 1-285aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanMouseRat |
| 应用 | WBIHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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