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产品简介
靶标 | ERLIN2 |
别名 | C8orf2; Chromosome 8 open reading frame 2; Endoplasmic reticulum lipid raft associated protein 2; Endoplasmic reticulum lipid raft-associated protein 2; ER lipid raft associated 2; ERLIN 2; Erlin-2; ERLIN2; ERLN2_HUMAN; HGNC:1356; MGC87072; NET32; SPFH 2; SPFH domain containing protein 2; SPFH domain family member 2; SPFH domain-containing protein 2; SPFH2; SPG18; Stomatin prohibitin flotillin HflC/K domain containing protein 2; Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2;;Erlin-2;NET32;SPFH2;SPG18;erlin-2 |
宿主 | Rabbit |
预测交叉反应 | Bovine; Orangutan; Zebrafish |
稀释比例 | WB 1:1000-3000.; IHC 1:50-200. |
Gene ID | 11160 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | O94905 |
蛋白分子量 | 17/23/38kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. |
亚细胞定位 | Cytoplasm |
免疫原 | Recombinant protein of human ERLIN2 |
亚型 | IgG |
纯化方法 | Octanoic acid-ammonium sulfate precipitation |
背景资料 | Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1. Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex. Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex. |
Public Immunogen Range | 1-153aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanMouseRat |
应用 | WBIHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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