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产品简介
| 靶标 | LSM6 |
| 别名 | U6 snRNA-associated Sm-like protein LSm6;Sm protein F;YDR378C;LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| 宿主 | Rabbit |
| 预测交叉反应 | A.thaliana |
| 稀释比例 | IHC 1:50-200. |
| Gene ID | 11157 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P62312 |
| 蛋白分子量 | 9kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | Recombinant protein of human LSM6 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) (PubMed:28781166).The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA (PubMed:10523320).Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway (Probable). |
| Public Immunogen Range | 1-81aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human;Mouse |
| 应用 | IHC |
| 规格 | 50ul100ul |
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