暂无数据
产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
产品简介
| 靶标 | PRKAG1 |
| 别名 | 5' AMP activated protein kinase gamma 1 subunit;5' AMP activated protein kinase subunit gamma 1;5''-AMP-activated protein kinase subunit gamma-1;AAKG1_HUMAN;AMP activated protein kinase noncatalytic gamma 1 subunit;AMPK gamma 1 chain;AMPK gamma1;AMPK subunit gamma-1;AMPKg;MGC8666;PRKAG 1;PRKAG1;Protein kinase AMP activated gamma 1 non catalytic subunit;protein kinase, AMP-activated, noncatalytic gamma-1 |
| 宿主 | Rabbit |
| 预测交叉反应 | Bovine;Pig |
| 稀释比例 | IHC 1:100-300. |
| Gene ID | 5571 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P54619 |
| 蛋白分子量 | 34/38/39kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. |
| 亚细胞定位 | Cytoplasm Nucleus Cell membrane |
| 免疫原 | Recombinant protein of human PRKAG1 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive. |
| Public Immunogen Range | 1-332aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human;Mouse;Rat |
| 应用 | IHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
暂无数据
我要询价
*联系方式：
(可以是QQ、MSN、电子邮箱、电话等，您的联系方式不会被公开)
*内容：
