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产品简介
| 靶标 | ATP6V0A2 |
| 别名 | a2;A2V ATPase;ARCL;ATP6a2;ATP6N1D;ATP6V0A2;ATPase, H+ transporting, lysosomal V0 subunit a isoform 2;ATPase, H+ transporting, lysosomal V0 subunit a2;Infantile malignant osteopetrosis;J6B7;Lysosomal H(+) transporting ATPase V0 subunit a2;Lysosomal H(+)-transporting ATPase V0 subunit a2;regeneration and tolerance factor;Stv1;TJ6;TJ6M;TJ6s;V ATPase 116 kDa isoform a2;V type proton ATPase 116 kDa subunit a;V type proton ATPase 116 kDa subunit a isoform 2;V-ATPase 116 kDa isoform a2;V-type proton ATPase 116 kDa subunit a isoform 2;Vacuolar proton translocating ATPase 116 kDa subunit a;Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2;Vph1;VPP2_HUMAN;WSS |
| 宿主 | Rabbit |
| 预测交叉反应 | Bovine |
| 稀释比例 | IHC 1:100-300. |
| Gene ID | 23545 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q9Y487 |
| 蛋白分子量 | 98kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. |
| 亚细胞定位 | Cytoplasm Cell membrane |
| 免疫原 | Recombinant protein of human ATP6V0A2 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Part of the proton channel of V-ATPases. Essential component of the endosomal pH-sensing machinery. May play a role in maintaining the Golgi functions, such as glycosylation maturation, by controlling the Golgi pH. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633). |
| Public Immunogen Range | 50-400aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human;Mouse |
| 应用 | IHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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