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| 靶标 | MYO10 |
| 别名 | myosin X;Unconventional myosin-X;Unconventional myosin-10;KIAA0799 |
| 宿主 | Rabbit |
| 预测交叉反应 | Bovine |
| 稀释比例 | WB 1:1000-3000.;IHC 1:100-300. |
| Gene ID | 4651 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q9HD67 |
| 蛋白分子量 | 11/164/237kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. |
| 亚细胞定位 | Cytoplasm Nucleus Cell membrane |
| 免疫原 | Recombinant protein of human MYO10 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles and functions as plus end-directed motor. The tail domain binds to membranous compartments containing phosphatidylinositol 3,4,5-trisphosphate or integrins, and mediates cargo transport along actin filaments. Regulates cell shape, cell spreading and cell adhesion. Stimulates the formation and elongation of filopodia. May play a role in neurite outgrowth and axon guidance. In hippocampal neurons it induces the formation of dendritic filopodia by trafficking the actin-remodeling protein VASP to the tips of filopodia, where it promotes actin elongation. Plays a role in formation of the podosome belt in osteoclasts. |
| Public Immunogen Range | 1-98aa |
| 克隆类型 | Polyclonal Antibody |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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