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产品简介
英文名称 | Anti-AKAP10 Polyclonal Antibody |
靶标 | AKAP10 |
别名 | AKAP-10;D-AKAP-2;PRKA10; |
宿主 | Rabbit |
稀释比例 | IHC 1:50-200. |
Gene ID | 11216 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | O43572 |
蛋白分子量 | 74kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasm |
免疫原 | A synthetic peptide of human AKAP10 |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase (By similarity). |
Public Immunogen Range | 25-75/662aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | Human |
应用 | IHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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