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产品简介
靶标 | DSG1 |
别名 | Cadherin family member 4;CDHF4;Desmoglein-1;Desmosomal glycoprotein 1;DG1;DGI;DSG;DSG1;DSG1_HUMAN;EPKHE;EPKHIA;Pemphigus foliaceus antigen;PPKS1;SPPK1 |
宿主 | Rabbit |
预测交叉反应 | Dog |
稀释比例 | IHC 1:100-300. |
Gene ID | 1828 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q02413 |
蛋白分子量 | 114kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. |
亚细胞定位 | Cell membrane Cytoplasm |
免疫原 | A synthetic peptide of human DSG1 |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. |
Public Immunogen Range | 730-780/1049aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | Human;Mouse |
应用 | IHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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