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产品简介
| 靶标 | NUDT1 |
| 别名 | MTH1 |
| 宿主 | Rabbit |
| 预测交叉反应 | A.thaliana;Dog |
| 稀释比例 | IHC 1:100-300. |
| Gene ID | 4521 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P36639 |
| 蛋白分子量 | 18/19/20/22kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | Recombinant protein of human NUDT1 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Antimutagenic. Plays a redundant role in sanitizing oxidized nucleotide pools, such as 8-oxo-dGTP pools. Acts as a sanitizing enzyme for oxidized nucleotide pools, thus suppressing cell dysfunction and death induced by oxidative stress. Hydrolyzes 8-oxo-dGTP, 8-oxo-dATP and 2-OH-dATP, thus preventing misincorporation of oxidized purine nucleoside triphosphates into DNA and subsequently preventing A:T to C:G and G:C to T:A transversions. Able to hydrolyze also the corresponding ribonucleotides, 2-OH-ATP, 8-oxo-GTP and 8-oxo-ATP. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA. |
| Public Immunogen Range | 1-180aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human Mouse Rat Predicted:A.thaliana Dog |
| 应用 | IHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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