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产品简介
| 靶标 | IPO5 |
| 别名 | IPO 5 ; IPO5 ; IPO5_HUMAN ; Karyopherin beta 3 ; Karyopherin beta-3 ; KPNB3 ; MGC2068 ; Pse1 ; Ran binding protein 5 ; Ran GTP binding protein 5 ; Ran-binding protein 5 ; RanBP 5 ; RanBP5 ; IMB3 ;KPNB3 ;Pse1 ;RANBP5 ;imp5 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:1000-3000. ;IHC 1:50-200. |
| Gene ID | 3843 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | O00410 |
| 蛋白分子量 | 117/124/126kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | Recombinant protein of human IPO5 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. |
| Public Immunogen Range | 1-350aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human ;Mouse |
| 应用 | WB IHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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