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| 靶标 | PTP4A2 |
| 别名 | PTP4A2 ;HH13 ;HH7-2 ;HU-PP-1 ;OV-1 ;PRL-2 ;PRL2 ;PTP4A ;PTPCAAX2 ;ptp-IV1a ;ptp-IV1b BM 008 ; EC 3.1.3.48 ; HH 13 ; HH13 ; HH7 2 ; HU PP 1 ; HUPP 1 ; HUPP1 ; OV 1 ; OV1 ; phosphatase of regenerating liver 2 ; PRL 2 ; PRL2 ; Protein tyrosine phosphatase 4a2 ; protein tyrosine phosphatase IVA ; protein tyrosine phosphatase IVA2 ; Protein tyrosine phosphatase of regenerating liver 2 ; protein tyrosine phosphatase type IVA 2 ; Protein tyrosine phosphatase type IVA member 2 isoform 1 ; protein tyrosine phosphatase type IVA, member 2 ; PTP (CAAXII) ; ptp IV1a ; ptp IV1b ; TP4A2_HUMAN |
| 宿主 | Rabbit |
| 稀释比例 | IHC 1:50-200. |
| Gene ID | 8073 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q12974 |
| 蛋白分子量 | 9/16/19kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. |
| 亚细胞定位 | Cytoplasm Cell membrane |
| 免疫原 | Recombinant protein of human PTP4A2 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17. |
| Public Immunogen Range | 1-168aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human ;Mouse ;Rat |
| 应用 | IHC |
| 规格 | 50ul100ul |
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