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产品简介
| 靶标 | PTPN6 |
| 别名 | HCP ;HCPH ;HPTP1C ;PTP-1C ;SH-PTP1 ;SHP-1 ;SHP-1L ;SHP1 ;CTCN6 ;PTPN6 ;PTP1C ;70Z-SHP ; EC 3.1.3.48 ; Hematopoietic cell phosphatase ; Hematopoietic cell protein tyrosine phosphatase ; Hematopoietic cell protein-tyrosine phosphatase ; HPTP1C ; Protein tyrosine phosphatase 1C ; Protein tyrosine phosphatase non receptor type 6 ; Protein tyrosine phosphatase SHP1 ; Protein-tyrosine phosphatase 1C ; protein-tyrosine phosphatase SHP 1 ; Protein-tyrosine phosphatase SHP-1 ; PTN6_HUMAN ; PTP 1C ; Ptpn6 ; SH PTP 1 ; SH PTP1 ; SH-PTP1 ; SHP 1 ; SHP 1L ; SHP1L ; tyrosine protein phosphatase non receptor type 6 ; Tyrosine-protein phosphatase non-receptor type 6 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:1000-3000. |
| Gene ID | 5777 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P29350 |
| 蛋白分子量 | 63/68/70kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | Recombinant protein of human PTPN6 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. |
| Public Immunogen Range | 1-350aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human ;Mouse ;Rat |
| 应用 | WB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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