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产品简介
靶标 | CYP3A4 |
别名 | CP33 ; CP34 ; CYP3A ; CYP3A3 ; CYP3A4 ; CYPIIIA4 ; Cytochrome P450 3A4 ; Cytochrome P450 family 3 subfamily A polypeptide 4 ; Cytochrome P450 subfamily IIIA polypeptide 3 ; Cytochrome P450 subfamily IIIA polypeptide 4 ; cytochrome P450, family 3, subfamily a, polypeptide 1 ; glucocorticoid inducible P450 ; HLP ; MGC126680 ; NF 25 ; NF25 ; Nifedipine oxidase ; Niphedipine oxidase ; P450 III steroid inducible ; P450 PCN(PCNC inducible) ; P450 PCN1 ; P450C3 ; P450PCN1 ; Quinine 3 monooxygenase ; Taurochenodeoxycholate 6 alpha hydroxylase ; CP3A4_HUMAN |
宿主 | Rabbit |
稀释比例 | WB 1:1000-3000. ;IHC 1:100-300. |
Gene ID | 1576 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q6GRK0 |
蛋白分子量 | 57kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. |
亚细胞定位 | Cytoplasm |
免疫原 | Recombinant protein of human CYP3A4 |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2-exo-monooxygenase. The enzyme also hydroxylates etoposide. |
Public Immunogen Range | 250-504aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | Human ;Rat |
应用 | WB IHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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