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产品简介
靶标 | P53 |
别名 | TP53;BCC7;LFS1;P53;TRP53;tumor protein p53 |
宿主 | Mouse |
稀释比例 | WB 1:1000-3000. |
Gene ID | 7157 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P04637 |
蛋白分子量 | 18/47/55/67kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Nucleus Cytoplasm |
亚型 | IgG1 |
纯化方法 | Octanoic acid-ammonium sulfate precipitation |
克隆号 | 3F12 |
背景资料 | This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). |
克隆类型 | Monoclonal Antibody |
交叉反应 | Human;Mouse |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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