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产品简介
| 靶标 | GPR125 |
| 别名 | FLJ38547; G protein coupled receptor 125; PGR21; Probable G protein coupled receptor 125 precursor; TEM5 like; TEM5L; GP125_HUMAN; GPCR125. |
| 宿主 | Rabbit |
| 预测交叉反应 | Human;Rat;Dog;Cow;Horse;Sheep |
| 稀释比例 | WB 1:500-2000;IHC 1:100-500;FCM=1μg/Test;IF 1:100-500;ELISA 1:5000-10000. |
| Gene ID | 166647 |
| 保存 | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Swiss Prot | Q8IWK6 |
| 蛋白分子量 | 143kDa |
| 储存液 | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
| 亚细胞定位 | Cell membrane; Multi pass membrane protein |
| 免疫原 | KLH conjugated synthetic peptide derived from human GPR125 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR125 (G protein-coupled receptor 125), also known as PGR21 or TEM5L, is a 1,321 amino acid multi-pass membrane protein belonging to the G-protein coupled receptor 2 family and the LN-TM7 subfamily. Considered a novel orphan adhesion-type G-protein-coupled receptor, GPR125 has five leucine rich repeats (LRR), an immunoglobulin (Ig) domain and a GPS domain. GPR125 may play a functional role in choroidal and hippocampal response to brain injury. It is also suggested that GPR125 may be a marker for spermatogonial stem cells. Four isoforms of GPR125 exists due to alternative splicing events. |
| Public Immunogen Range | 422-530/1321aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Mouse |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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